Restylane® Defyne (1x1ml)

Original price was: €124.99.Current price is: €110.00.

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Volume Discount
20+ packs: Save 1% 108.90

The pack consists of:

1 x 1ml syringe
2 x 27G 1/2″ needles
20 mg/ml Cross-linked hyaluronic acid
3 mg/ml Lidocaine

For more information click here

For more information click here


Restylane Defyne is a dermal filler that is designed to address moderate to severe facial wrinkles and folds, such as nasolabial folds and marionette lines. It is made from hyaluronic acid, a naturally occurring substance in the body that helps to hydrate and plump the skin.

Restylane Defyne is unique in that it is formulated with XpresHAn Technology™, which allows the filler to move with the natural expressions of the face while maintaining its shape and structure. This means that patients can achieve a more natural-looking result that doesn’t appear stiff or frozen.

Restylane Defyne is injected into the treatment area using a fine needle. The procedure is typically quick and relatively painless, and patients can return to their normal activities immediately after treatment. Results can last up to 12 months or longer, depending on the individual and the treatment area.

Like all injectable treatments, Restylane Defyne should only be administered by a qualified and experienced healthcare professional. Possible side effects may include bruising, swelling, redness, and tenderness at the injection site, but these are typically mild and resolve on their own within a few days.

Benefits of Restylane Defyne

Benefits of Restylane Defyne include:

  1. Natural-Looking Results: Restylane Defyne is formulated with XpresHAn Technology, which allows for a range of flexibility and support while maintaining a natural look. This means that when you move your face, the filler moves with you, preventing a “stiff” or unnatural appearance.
  2. Immediate Results: Like other HA fillers, the results of Restylane Defyne are visible immediately after injection, allowing patients to see instant improvements in the treated areas.
  3. Long-Lasting: The effects of Restylane Defyne can last up to 12 months or longer, depending on individual factors like metabolism, the area treated, and injection technique.
  4. Reversible: Since it’s a hyaluronic acid-based filler, any unwanted results or complications can be addressed using an enzyme called hyaluronidase, which dissolves the filler.
  5. Safety Profile: As with all FDA-approved products, Restylane Defyne has undergone rigorous clinical testing to ensure its safety. While there are potential side effects (like swelling, redness, and bruising at the injection site), they’re generally temporary.
  6. Non-Surgical: Restylane Defyne provides an option for individuals who want to address signs of aging without undergoing surgical procedures. The injections are relatively quick, and the recovery time is minimal compared to surgical interventions.
  7. Hydration: Since hyaluronic acid is a natural substance found in the skin that retains water, Restylane Defyne can also help to hydrate the skin, providing a refreshed look.
  8. Biocompatible and Non-Animal Based: Hyaluronic acid, the main component of Restylane Defyne, is naturally found in the human body, which reduces the risk of allergic reactions. Moreover, it is synthesized in a lab and is not derived from animal sources.

Areas of Use

Restylane Defyne is FDA-approved for the correction of moderate to severe facial wrinkles and folds, including nasolabial folds (the lines that run from the nose to the corners of the mouth) and marionette lines (the lines that run from the corners of the mouth to the chin).

However, it can also be used off-label for other areas, such as enhancing the chin, correcting the contours of the jawline, or plumping up the lips. Your healthcare provider will be able to assess your individual needs and recommend the best treatment plan for you.

It’s important to note that Restylane Defyne, like all dermal fillers, is not recommended for use in individuals with a history of severe allergic reactions or hypersensitivity to hyaluronic acid, or in those with bleeding disorders or active infections in the treatment area. It’s always best to consult with a qualified healthcare provider to determine if Restylane Defyne is the right treatment for you.


Restylane Defyne is made from hyaluronic acid, which is a naturally occurring substance in the body that helps to hydrate and plump the skin. The hyaluronic acid in Restylane Defyne is produced through a process called NASHA (Non-Animal Stabilized Hyaluronic Acid) technology, which involves cross-linking the hyaluronic acid molecules to create a gel-like substance that can be injected into the skin.

In addition to hyaluronic acid, Restylane Defyne also contains lidocaine, which is a local anesthetic that helps to minimize discomfort during the injection process.

Restylane Defyne is free from animal products and does not require any allergy testing prior to treatment. It is biodegradable and eventually breaks down naturally within the body. Overall, the ingredients in Restylane Defyne are well-tolerated by most patients, making it a safe and effective option for facial rejuvenation.

Restylane Defyne FAQs

1. What is Restylane Defyne?

  • Answer: Restylane Defyne is a hyaluronic acid-based dermal filler specifically formulated to address moderate to severe deep facial wrinkles and folds, offering a more youthful appearance while maintaining natural facial expressions.

2. How does it differ from other fillers?

  • Answer: Restylane Defyne uses XpresHAn Technology, allowing for flexibility and providing a smooth, natural look, especially when the face is in motion.

3. How long do results last with Restylane Defyne?

  • Answer: The results can last up to 12 months or even longer. However, individual results may vary based on factors like metabolism, lifestyle, and the area treated.

4. Are there any side effects?

  • Answer: Common side effects include swelling, redness, pain, bruising, and tenderness at the injection site. Most side effects are mild and will resolve within a week or two.

5. How soon can I return to my daily activities after the treatment?

  • Answer: Most patients can resume their usual activities immediately after the treatment. However, it’s generally recommended to avoid intense physical activity for the first 24-48 hours.

6. Is the procedure painful?

  • Answer: Restylane Defyne contains lidocaine, an anesthetic, to improve comfort during the injection. Some patients might experience mild discomfort, but it’s generally well-tolerated.

7. Who should not use Restylane Defyne?

  • Answer: Individuals with severe allergies, history of allergic reactions to lidocaine or gram-positive bacterial proteins, or those with bleeding disorders should avoid using Restylane Defyne. Always consult with a medical professional before undergoing treatment.

8. Can Restylane Defyne be combined with other treatments?

  • Answer: It can be combined with other treatments, but it’s essential to consult with a dermatologist or cosmetic surgeon to ensure the best results and safety.

9. Is there any downtime after the injection?

  • Answer: There’s minimal downtime. Some patients might experience mild swelling or redness, but these side effects typically subside within a few days.

10. How much does Restylane Defyne treatment cost?

  • Answer: The cost of Restylane Defyne varies based on geographic location, the expertise of the provider, and the amount of product required. It’s recommended to get a personalized quote from a local clinic or medical professional.

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